11/14/2022 0 Comments Region x hair![]() The red hair color is very rare around the world. The mutation of the SNP or adenine-guanine nucleotide has been marked as a potential element of blond hair phenotype. Genes involved in the pigment production contain single-nucleotide polymorphisms (SNP) or the adenine guanine nucleotide, which alters the amount of KITLG present in the hair follicle. #Region x hair skin#KIT ligand along with other genes is responsible for the mutation of skin color, blood stem cells, and sperm. The genome-wide association studies (GWAS) has found that the mutant gene that is responsible for blondness in the Northern European population is KIT ligand (KITLG), which has an ability to fight skin cancer. People with blond hair color are mostly seen in European countries. Blond Hair Colorīlond hair is formed when there is a presence of lower quantity of brown eumelanin with the absence of other pigments. Based on this allele-enzyme activity, the shade of brown hair color differs. Some alleles in people with brown-Swedish blond suppress the enzyme production, which in turn causes less production of brown pigment. These many shades of brown are due to the presence of an allele, a specific variation in the gene that is found at the specific spot on the chromosome.įor example, people with brown-ebony shaded hair have some alleles that catalyze the enzymes to produce a large amount of brown pigment. Human hair in brown color is seen in many shades like brown-ebony, brown-mahogany, brown-oak, etc. Black Hair Colorīlack is the commonly seen hair color in Asia and Africa due to the fact that the people in these regions tend to have lower levels of tyrosinase in their bodies.īlack eumelanin secretion causes the hair to turn black, which indicates that the MC1R is in the active state. Among these major colors, different shades also exist. Predominantly, human hair can be of five different colors: black, brown, blond, white/gray, and rarely red. Mutation of neuromelanin may result in a neurodegenerative disorder, which has an indirect relation with hair color. Since it is found in dopamine neurons, it colors some areas of the brain, which has no direct relation with hair color. This pigment lacks the feature of protecting the skin from sunlight. When MC1R is in an inactive condition, the melanocytes will produce pheomelanin, which causes light or red hair. It is also responsible for the protection of skin from damage by ultraviolet radiation. When MC1R is in the active condition, it produces eumelanin, which causes dark hair. There are three types of natural melanin. It is found on the surface of melanocytes and also in other cells and play a role in the immune function in humans. Melanocortin 1 Receptor (MC1R) is the gene responsible for hair color determination. The color of the hair depends on the amount and type of melanin produced by melanocytes. Melanins are pigments derived from an amino acid called tyrosine. Image Credit: Subbotina Anna / Shutterstock Melanin ![]()
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